目录号： 100018
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关键信息
Liquid, may turn slightly opaque during stroage
Human
CLIA,FIA,LF
产品概述
| 产品名称 | Anti-h LH 5302 SP-1 |
|---|---|
| 目录号 | 100018 |
| 描述 | Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components. |
| 应用 | CLIA,FIA,LF, 若需了解更多应用，请联系我们 |
补充说明
| 剂型/外观 | Liquid, may turn slightly opaque during stroage |
|---|---|
| 浓度 | 1.0 mg/ml (+/- 10 %) |
| 备注 | In Nilsson et al. (2001) authors performed an epitope mapping analysis of 30 different monoclonal antibodies for LH. In their analysis it was shown that 5302 binds to an epitope named as beta 1. Antibodies reacting with beta 1 epitope did not react with FSH. They also showed that 5302 reacts with intact LH as well as with beta-subunit of LH while having some cross-reactivity with hCG but no cross reactivity with TSH or FSH. Clone 5302 reacted also with variant-LH. |
| 抗体亚型 | IgG1 |
| 克隆性质 | Monoclonal |
| 抗原决定簇 | Beta 1 as described in Nilsson et al. (2001). Two antibodies binding to the same, or closely located epitopes, belong to the same group and hence cannot be used as a pair in a sandwich assay. Epitope group numbering does not give any detailed information where the epitope is located. |
| 纯度 | ≥ 95 % |
| 亲和常数 | KA= 4.8 x 1010 1/M; KD= 2.1 x 10-11 M ( = 21 pM) |
| 相关产品 | Native LH antigen Lee Biosolutions 996-31 |
| 缓冲液 | 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| 等电聚焦图谱 | 5.6–6.3 |
| 交叉反应 | LH α 10 %, LH β 127 %, FSH 3 %, hCG 4 %, TSH 0.02 % |
| 特异性 | Antibody recognizes human luteinizing hormone (lutropin), and its beta-subunit |
储运条件
| 储存条件 | +2-8°C |
|---|---|
| 运输条件 | Cold packs |
| 库存及货期 | 小包装样品现货 |
| 有效期 | 36 months |
参考文献
| 文献 | Federici, M.M., Fraser, R., Lundqvist, C., and Lankford, J.C., (1982) Production and characterization of monoclonal antibodies human lutenizing hormones. Fed. Proc., 41 Nilsson, C., Seppälä, M., and Pettersson, K., (2001) Immunological characterization of human luteinizing hormone with special regard to a common genetic variant. J.Endocrinol. 168:10-116 |
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