目录号： 100139
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关键信息
Liquid, may turn slightly opaque during stroage
Human
FIA
产品概述
| 产品名称 | Anti-h PSA 8312 SPRN-5 |
|---|---|
| 目录号 | 100139 |
| 描述 | Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components. |
| 应用 | FIA, 若需了解更多应用，请联系我们 |
补充说明
| 剂型/外观 | Liquid, may turn slightly opaque during stroage |
|---|---|
| 浓度 | 5.0 mg/ml (+/- 10 %) |
| 备注 | Clone 8312 reacts with non-reduced and reduced intact PSA as well as with reduced PSA fragments (Rye et al., 1999). In the same study affinities for free-PSA and PSA-ACT-complex were, 7.5 x 10-9 mol/l and 1.03 x 10-10, respectively. They also noted that antibodies binding to epitope group 6 form a good pair with antibodies from groups 1 and 3. Clone 8312 crossreacts with human kallikrein-2 (Rye, 1999a). Clone 8312 was coded as 5E4 in Rye et al. (1999). |
| 抗体亚型 | IgG1 |
| 克隆性质 | Monoclonal |
| 抗原决定簇 | Residues 3–11, group 6a as described in Rye et al. (1999) |
| 纯度 | ≥ 95 % |
| 亲和常数 | KA= 3 x 109 1/M |
| 相关产品 | Native PSA antigen, Lee Biosolutions 497-11 and 497-17 |
| 缓冲液 | 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| 等电聚焦图谱 | 6.3–7.0 |
| 交叉反应 | PSA/α1-ACT complex 15 %. Does not recognize human kallikrein-2 or PAP. |
| 特异性 | Antibody recognizes human prostate-specific antigen |
储运条件
| 储存条件 | +2-8°C |
|---|---|
| 运输条件 | Cold packs |
| 库存及货期 | 小包装样品现货 |
| 有效期 | 36 months |
参考文献
| 文献 | Rye, P.D., Bormer, O.P. and Paus, E. (guest editors) (1999), ISOBM TD-3 International Workshop on monoclonal antibodies against prostate-specific antigen. Tumor Biol., 20(suppl 1):1-94 |
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